Salmon DNA

Salmon DNA treatments at Yofi Med Spa in Philadelphia, PA are designed to improve hydration, smooth skin texture, and calm sensitivity without adding volume. Schedule your appointment today.

Restore Skin Quality with Salmon DNA

This treatment uses purified polynucleotides (PN or PDRN) to support hydration, refine texture, and calm irritation at the skin level. A Salmon DNA treatment is often chosen for dull, sensitive, or post-summer skin that needs a reset, helping to restore a natural, radiant glow.

Options include Salmon DNA microneedling sessions for targeted renewal or Salmon DNA injections to deliver hydration more directly.

As part of your overall Salmon DNA skincare plan, these treatments improve comfort and appearance without adding volume, making them ideal before weddings or special occasions.

Top Benefits of Salmon DNA

Boosts Skin Hydration

Improves moisture retention for plumper, healthier-looking skin. This helps restore balance in dry or tired skin, leaving it soft and supple.

Refines Skin Quality

Smooths texture and calms sensitivity without altering facial volume. It supports a more even tone and comfortable feel, making skin look refreshed.

Event-Ready Glow

Minimal downtime makes it ideal before weddings or special occasions. You can return to your routine quickly while enjoying a natural, radiant glow.

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Everything You Need to Know About Salmon DNA

  • What is it?
    Polynucleotides (PN), sometimes called PDRN. They support hydration and the appearance of smoother, calmer skin.
  • Will it change how I look?
    No volume change—this targets skin quality.
  • How many sessions?
    Many see best results with 3 sessions, ~3–4 weeks apart; maintenance every 4–6 months.
  • Downtime?
    Possible pin-point bumps/redness for 1–3 days. Plan 1–2 weeks before events.
  • Does it hurt?
    Mild; numbing and comfort measures available.
  • Combine with?
    Microneedling (separate days), LED, gentle facials, SPF.
  • Sensitive skin?
    Often chosen for reactive skin; barrier assessment first.

Woman with dark hair and bare shoulders smiles, hands near face, eyes closed.

Myth vs. Fact

There are a few common misconceptions about Salmon DNA treatments. Here’s the truth behind some of the most frequent myths:

  • Myth: “It’s literally raw salmon in my face.”
    Fact: It refers to polynucleotides; some brands source from fish DNA fragments but the final product is purified and formulated for skin use.
  • Myth: “It works like filler.”
    Fact: No—it supports skin quality; it doesn’t add structure/volume.
  • Myth: “One session, forever results.”
    Fact: Best with a short series and periodic maintenance.

Frequently Asked Questions

Explore our detailed FAQs to learn more about Salmon DNA. For any additional questions, please feel free to reach out to us directly.

What Our Clients Are Saying

Explore our detailed FAQs to learn more about Salmon DNA. For any additional questions, please feel free to reach out to us directly.

Want healthier, smoother skin with Salmon DNA?

Enhance your skin’s hydration and texture with Salmon DNA, along with treatments such as Neurotoxins , PRP Facial Balancing , Skin Tightening , Body Contouring , Dermal Fillers , and Radiesse to support your overall skin goals.